CPT 75893Radiology

Venous sampling by catheter

CPT 75893 covers the procedure where a doctor inserts a catheter into a vein to collect blood samples from specific locations in the body. This is typically done to measure hormone levels or other substances at their source to diagnose conditions affecting glands or organs.

Showing rates for

National Average

Base Medicare rate

$102.21

This calculator gives a typical-case estimate using standard Medicare modifier rules. Actual payment depends on payer policies, documentation, code-specific CMS status indicators, and locality. Verify before billing.

RVU breakdown

Work RVU

0.54

PE RVU (NF)

2.56

MP RVU

0.06

Total RVU

3.16

Conversion factor: 32.3465 · Source: CMS MPFS RVU25A · Confidence: High

NCCI bundling edits

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Billing tips

Always bill 75893 separately from the catheter placement code (36010, 36011, or 36012) as the venous sampling represents additional work beyond basic vascular access
Impact: Prevents loss of $102.21 reimbursement; many billers incorrectly assume sampling is included in catheter placement
Document the specific venous location(s) sampled and the number of separate sampling sites, as multiple samplings may justify modifier 50 or additional units
Impact: Bilateral adrenal vein sampling with modifier 50 can increase reimbursement by approximately $51.11 (50% additional payment)
Ensure the operative report clearly distinguishes between diagnostic venography (75831-75833) and venous sampling, as these are separate billable services
Impact: Allows stacking of both diagnostic imaging and sampling codes, potentially adding $150-300 in additional revenue per case
When billing with ACTH stimulation during adrenal vein sampling, document timing and medical necessity of stimulation protocol to support separate E/M or drug administration codes
Impact: ACTH administration and monitoring can add $75-150 in additional reimbursement when properly documented
Use place of service code 22 (on-campus outpatient hospital) rather than 21 (inpatient) when appropriate, as this reflects the non-facility rate accurately
Impact: Ensures proper reimbursement at $102.21; incorrect POS codes can trigger audits or payment adjustments
Submit with ICD-10 codes that clearly establish medical necessity for venous sampling (E26.09 for primary aldosteronism, E24.0 for Cushing's disease, E21.0 for primary hyperparathyroidism)

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Frequently asked questions

What is the Medicare reimbursement rate for CPT code 75893 in 2025?

The 2025 Medicare national average payment for CPT 75893 is $102.21 for both facility and non-facility settings. This rate is based on 3.16 total RVUs multiplied by the 2025 conversion factor of 32.3465.

Can CPT 75893 be billed bilaterally with modifier 50?

Yes, CPT 75893 can be billed with modifier 50 when bilateral venous sampling is performed, such as sampling from both adrenal veins for aldosteronism lateralization. Medicare typically reimburses bilateral procedures at 150% of the base rate, which would be approximately $153.32.

Is CPT 75893 bundled with catheter placement codes?

CPT 75893 is not automatically bundled with selective catheter placement codes (36010-36012) and should be billed separately, as the venous sampling represents additional diagnostic work beyond vascular access. However, you may need to append modifier 59 or XU to prevent NCCI bundling edits from some payers.

What diagnosis codes support medical necessity for CPT 75893?

Common ICD-10 codes supporting 75893 include E26.09 (other primary aldosteronism), E24.0 (pituitary-dependent Cushing's disease), E21.0 (primary hyperparathyroidism), and D44.1 (neoplasm of adrenal gland). The diagnosis should reflect confirmed biochemical abnormality requiring anatomical localization.

How many RVUs is CPT code 75893 worth in 2025?

CPT 75893 has a total of 3.16 RVUs in 2025, consisting of 0.54 work RVUs, 2.56 practice expense RVUs, and 0.06 malpractice RVUs. These values are the same for both facility and non-facility settings.

What specialties typically bill CPT code 75893?

CPT 75893 is primarily billed by interventional radiologists and vascular surgeons who perform catheter-based venous sampling procedures. Neurointerventional radiologists also bill this code for petrosal sinus sampling in Cushing's disease workup.

Can CPT 75893 be billed multiple times on the same day?

CPT 75893 can potentially be billed multiple times if sampling is performed at distinctly different venous locations requiring separate catheterizations, though this is uncommon. More typically, bilateral sampling is reported once with modifier 50. Use modifier 76 for repeat sampling due to technical failure, with clear documentation of medical necessity.