E88.4

Mitochondrial metabolism disorders

Diagnosis reference

Nonbillable category

This entry is a category or subcategory. Choose the appropriate billable descendant based on the clinical documentation.

Effective periodOctober 1, 2026–September 30, 2027

SourceCMS ICD-10-CM order file

ClassificationDiagnosis · clinical modification

Related entries

Up to 30 descendants in this category

CODE	DESCRIPTION	TYPE
E88.40	Mitochondrial metabolism disorder, unspecified	Billable
E88.41	MELAS syndrome	Billable
E88.42	MERRF syndrome	Billable
E88.43	Disorders of mitochondrial tRNA synthetases	Billable
E88.49	Other mitochondrial metabolism disorders	Billable

Use the complete reference

This reference does not reproduce the full tabular hierarchy, inclusion notes, Excludes1/2 notes, sequencing instructions, or seventh-character rules. Review the official tables and coding guidelines.

Open official CMS files

ICD-10-CM codes describe diagnoses. They do not have an independent Medicare PFS reimbursement amount, and billability alone does not establish coverage.