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ICD-10-CM · FY 2026 APRIL UPDATE

D57

Sickle-cell disorders

Diagnosis reference

Nonbillable category

This entry is a category or subcategory. Choose the appropriate billable descendant based on the clinical documentation.

Effective periodOctober 1, 2026–September 30, 2027
SourceCMS ICD-10-CM order file
ClassificationDiagnosis · clinical modification

Related entries

Up to 30 descendants in this category

CODEDESCRIPTIONTYPE
D57.0Hb-SS disease with crisisCategory
D57.00Hb-SS disease with crisis, unspecifiedBillable
D57.01Hb-SS disease with acute chest syndromeBillable
D57.02Hb-SS disease with splenic sequestrationBillable
D57.03Hb-SS disease with cerebral vascular involvementBillable
D57.04Hb-SS disease with dactylitisBillable
D57.09Hb-SS disease with crisis with other specified complicationBillable
D57.1Sickle-cell disease without crisisBillable
D57.2Sickle-cell/Hb-C diseaseCategory
D57.20Sickle-cell/Hb-C disease without crisisBillable
D57.21Sickle-cell/Hb-C disease with crisisCategory
D57.211Sickle-cell/Hb-C disease with acute chest syndromeBillable
D57.212Sickle-cell/Hb-C disease with splenic sequestrationBillable
D57.213Sickle-cell/Hb-C disease with cerebral vascular involvementBillable
D57.214Sickle-cell/Hb-C disease with dactylitisBillable
D57.218Sickle-cell/Hb-C disease with crisis with other specified complicationBillable
D57.219Sickle-cell/Hb-C disease with crisis, unspecifiedBillable
D57.3Sickle-cell traitBillable
D57.4Sickle-cell thalassemiaCategory
D57.40Sickle-cell thalassemia without crisisBillable
D57.41Sickle-cell thalassemia, unspecified, with crisisCategory
D57.411Sickle-cell thalassemia, unspecified, with acute chest syndromeBillable
D57.412Sickle-cell thalassemia, unspecified, with splenic sequestrationBillable
D57.413Sickle-cell thalassemia, unspecified, with cerebral vascular involvementBillable
D57.414Sickle-cell thalassemia, unspecified, with dactylitisBillable
D57.418Sickle-cell thalassemia, unspecified, with crisis with other specified complicationBillable
D57.419Sickle-cell thalassemia, unspecified, with crisisBillable
D57.42Sickle-cell thalassemia beta zero without crisisBillable
D57.43Sickle-cell thalassemia beta zero with crisisCategory
D57.431Sickle-cell thalassemia beta zero with acute chest syndromeBillable

Use the complete reference

This reference does not reproduce the full tabular hierarchy, inclusion notes, Excludes1/2 notes, sequencing instructions, or seventh-character rules. Review the official tables and coding guidelines.

Open official CMS files

ICD-10-CM codes describe diagnoses. They do not have an independent Medicare PFS reimbursement amount, and billability alone does not establish coverage.